| ImmunCR Id : | ICR57 |
| Chemical Name : | Choline |
| Plant Source : | Carica papaya |
| Nutraceutical information : | Edible, Almonds, Shitake mushroom, Brussels sprouts, wheat germ |
| Mode of administration : | Oral, capsules, extended release tablets |
| Immunomodulatory mechanism : | Anti-inflammatory (reduction in IL-6); activation of IL-1β, IL-18 |
| Description : | Choline is an essential nutrient produced in small amounts in the body through the hepatic phosphatidylethanolamine N-methyltransferase pathway and an integral part of cell signaling, integrity and other metabolic activities, also responsible for better functioning and repair of the brain, liver and muscles. |
| IUPAC Name | 2-hydroxyethyl(trimethyl)azanium |
| SMILES | C[N+](C)(C)CCO |
| Formula | C5H14NO+ |
| InchiKey | OEYIOHPDSNJKLS-UHFFFAOYSA-N |
| Kingdom | Organic compounds |
| Superclass | Organic nitrogen compounds |
| Class | Organonitrogen compounds |
| Subclass | Quaternary ammonium salts |
| LogP | -1.575 |
| Molecular weight | 104.171 |
| Hydrogen Bond Acceptor | 1 |
| Hydrogen Bond Donor | 1 |
| Polar surface area | 20.815 |
| No. of rotatable bonds | 2 |
| Number of Aromatic Rings | 0 |
| Number of rings | 0 |
| Absorption level | low |
| Solubility level | Very Soluble |
| Blood Brain Barrier | Undefined |
| Plasma protein binding | Non-Binder |
| CYP2D6 inhibition | Inhibitor |
