| ImmunCR Id : | ICR145 |
| Chemical Name : | Eriocitrin |
| Plant Source : | Cyclopia subternata, Citrus latipes |
| Nutraceutical information : | It is marketed as a dietary supplement, usually in conjunction with B and C vitamins and other substances |
| Mode of administration : | --- |
| Immunomodulatory mechanism : | Eriocitrin has been reported to pose immunomodulatory properties against lung cancer |
| Description : | Eriocitrin is a disaccharide derivative that consists of eriodictyol substituted by a 6-O-(alpha-L-rhamnopyranosyl)-beta-D-glucopyranosyl moiety at position 7 via a glycosidic linkage. It has a role as an antioxidant. It is a disaccharide derivative, a member of 3-hydroxyflavanones, a trihydroxyflavanone, a flavanone glycoside, a member of 4-hydroxyflavanones and a rutinoside. It is functionally related to an eriodictyol. |
| IUPAC Name | (2S)-2-(3,4-dihydroxyphenyl)-5-hydroxy-7-[(2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-[[(2R,3R,4R,5R,6S)-3,4,5-trihydroxy-6-methyloxan-2-yl]oxymethyl]oxan-2-yl]oxy-2,3-dihydrochromen-4-one |
| SMILES | C[C@H]1[C@@H]([C@H]([C@H]([C@@H](O1)OC[C@@H]2[C@H]([C@@H]([C@H]([C@@H](O2)OC3=CC(=C4C(=O)C[C@H](OC4=C3)C5=CC(=C(C=C5)O)O)O)O)O)O)O)O)O |
| Formula | C27H32O15 |
| InchiKey | OMQADRGFMLGFJF-MNPJBKLOSA-N |
| Kingdom | Organic compounds |
| Superclass | Phenylpropanoids and polyketides |
| Class | Flavonoids |
| Subclass | Flavonoid glycosides |
| LogP | -0.657 |
| Molecular weight | 596.534 |
| Hydrogen Bond Acceptor | 15 |
| Hydrogen Bond Donor | 9 |
| Polar surface area | 249.29 |
| No. of rotatable bonds | 6 |
| Number of Aromatic Rings | 2 |
| Number of rings | 5 |
| Absorption level | Very low |
| Solubility level | Very Soluble |
| Blood Brain Barrier | Undefined |
| Plasma protein binding | Non-Binder |
| CYP2D6 inhibition | Non-Inhibitor |
