ImmunoCR
A repository of plant based immunomodulatory compounds
ImmunoCR
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Nutraceutical Profile

ImmunCR Id : ICR134
Chemical Name : Arachidonic acid
Plant Source : Poultry, animal organs and meat, fish, seafood, and eggs
Nutraceutical information : ---
Mode of administration : ---
Immunomodulatory mechanism : ARA promotes and regulates type 2 immune responses against intestinal and blood flukes and may well represent an invaluable endoschistsomicide and endotumoricide
Description : Arachidonic Acid is an unsaturated, essential fatty acid. It is found in animal and human fat as well as in the liver, brain, and glandular organs, and is a constituent of animal phosphatides. It is formed by the synthesis from dietary linoleic acid and is a precursor in the biosynthesis of prostaglandins, thromboxanes, and leukotrienes.(ChemID Plus)

Chemical Structure Information

IUPAC Name (5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid
SMILES CCCCC/C=CC/C=CC/C=CC/C=CCCCC(=O)O
Formula C20H32O2
InchiKey YZXBAPSDXZZRGB-DOFZRALJSA-N

Chemical Classification

Kingdom Organic compounds
Superclass Lipids and lipid-like molecules
Class Fatty Acyls
Subclass Fatty acids and conjugates

Physicochemical properties

LogP 6.439
Molecular weight 304.467
Hydrogen Bond Acceptor 2
Hydrogen Bond Donor 1
Polar surface area 38.116
No. of rotatable bonds 14
Number of Aromatic Rings 0
Number of rings 0

ADMET Properties

Absorption level Moderate
Solubility level Very Soluble
Blood Brain Barrier Very High
Plasma protein binding Binder
CYP2D6 inhibition Non-Inhibitor

Other Biological Properties

  • ---

References

    1. https://doi.org/10.1016/j.jare.2017.11.004


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