ImmunoCR
A repository of plant based immunomodulatory compounds
ImmunoCR
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Nutraceutical Profile

ImmunCR Id : ICR131
Chemical Name : Hydroxycitric acid
Plant Source : Garcinia cambogia
Nutraceutical information : Used as weight loss supplement
Mode of administration : ---
Immunomodulatory mechanism : HCA decreased the production of NO probably by suppressing the expression of iNOS and TNF-α
Description : Hydroxycitric acid is a carbonyl compound.

Chemical Structure Information

IUPAC Name 1,2-dihydroxypropane-1,2,3-tricarboxylic acid
SMILES C(C(=O)O)C(C(C(=O)O)O)(C(=O)O)O
Formula C6H8O8
InchiKey ZMJBYMUCKBYSCP-UHFFFAOYSA-N

Chemical Classification

Kingdom Organic compounds
Superclass Organic acids and derivatives
Class Carboxylic acids and derivatives
Subclass Tricarboxylic acids and derivatives

Physicochemical properties

LogP -1.971
Molecular weight 208.123
Hydrogen Bond Acceptor 8
Hydrogen Bond Donor 5
Polar surface area 155.979
No. of rotatable bonds 5
Number of Aromatic Rings 0
Number of rings 0

ADMET Properties

Absorption level Very low
Solubility level Very Soluble
Blood Brain Barrier Undefined
Plasma protein binding Non-Binder
CYP2D6 inhibition Non-Inhibitor

Other Biological Properties

  • ---

References

    1. https://doi.org/10.4103/1673-5374.193240
    2. https://doi.org/10.1155/2011/509038


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