| ImmunCR Id : | ICR125 |
| Chemical Name : | alpha-Pinene |
| Plant Source : | Rosemary |
| Nutraceutical information : | --- |
| Mode of administration : | Oil |
| Immunomodulatory mechanism : | α-pinene exhibited the strongest prevention against IL-1β-stimulated inflammatory and catabolic pathways. α-pinene reduced IL-6 and TNF-α formation in macrophages of rats. It was also found that nitrite production was reduced by α-pinene. |
| Description : | Alpha-pinene appears as a clear colorless liquid with a turpentine odor. Flash point 91°F. Less dense than water and insoluble in water. Vapors are heavier than air. Used as a solvent. |
| IUPAC Name | 2,6,6-trimethylbicyclo[3.1.1]hept-2-ene |
| SMILES | CC1=CCC2CC1C2(C)C |
| Formula | C10H16 |
| InchiKey | GRWFGVWFFZKLTI-UHFFFAOYSA-N |
| Kingdom | Organic compounds |
| Superclass | Lipids and lipid-like molecules |
| Class | Prenol lipids |
| Subclass | Monoterpenoids |
| LogP | 2.872 |
| Molecular weight | 136.234 |
| Hydrogen Bond Acceptor | 0 |
| Hydrogen Bond Donor | 0 |
| Polar surface area | 0 |
| No. of rotatable bonds | 0 |
| Number of Aromatic Rings | 0 |
| Number of rings | 3 |
| Absorption level | Good |
| Solubility level | Very Soluble |
| Blood Brain Barrier | Very High |
| Plasma protein binding | Binder |
| CYP2D6 inhibition | Non-Inhibitor |
